Twenty patients with severe neuropathic (Charcot) ankle deformities un
derwent 21 attempted ankle fusions with a retrograde locked intramedul
lary nail as an alternative to amputation, Ail had insensate heel pads
and had failed at nonoperative methods of accommodative ambulatory br
acing. In 11, the talus was either absent, or the deformity was of suf
ficient magnitude to require talectomy to align the calcaneus under th
e tibia for plantigrade weightbearing. Ages ranged from 28 to -68 (ave
rage 56.3) years. Nineteen were diabetic, 12 being insulin-dependent,
Their average body weight was 102 kg, with 11 greater than 90 kg at th
e time of surgery. Eight had chronic large full thickness ulcers overl
ying, but not involving bone of the medial malleolus, medial midfoot,
or proximal fifth metatarsal, at the time of surgery. At a follow-up o
f 12 to 31 months, 19 achieved bony fusion. In the 10 patients where t
alectomy was not required, fusion was achieved at an average of 5.3 mo
nths without complications. In the patients who required talectomy, si
x of the patients required eight additional operations to achieve fusi
on. Three achieved fusion following removal of the nail and prolonged
bracing. One opted for ankle disarticulation for chronic persistent in
fection, rather than attempt reoperation. One died of unrelated causes
during the early postoperative period. Retrograde locked intramedulla
ry ankle fusion is a reasonable alternative to amputation in the neuro
pathic (Charcot) ankle that cannot be controlled with standard bracing
techniques. The potential for morbidity requiring reoperation is grea
tly increased when the deformity is of sufficient magnitude to require
talectomy to achieve alignment of the calcaneus in a plantigrade weig
ht-bearing position under the tibia or when there are large open ulcer
s.