THE SYSTEM OF SULFATED ALPHA-(1-]3)-LINKED D-MANNANS FROM THE RED SEAWEED NOTHOGENIA-FASTIGIATA - STRUCTURES, ANTIHERPETIC AND ANTICOAGULANT PROPERTIES
Aa. Kolender et al., THE SYSTEM OF SULFATED ALPHA-(1-]3)-LINKED D-MANNANS FROM THE RED SEAWEED NOTHOGENIA-FASTIGIATA - STRUCTURES, ANTIHERPETIC AND ANTICOAGULANT PROPERTIES, Carbohydrate research, 304(1), 1997, pp. 53-60
Structural analysis of two xylomannans extracted from Nothogenia fasti
giata was carried out. The results are consistent with the general pat
tern previously reported for other xylo-mannans of the same system, al
pha-(1 --> 3)-linked D-mannans 2- and 6-sulfated and having single stu
bs of beta-(1 --> 2)-linked D-xylose, but one of the new samples conta
ins a significant amount of 2,6-disulfated units. Both xylomannans stu
died are obtained as complexes with a beta-D-(1 --> 3)-, alpha-L-(1 --
> 4)-galactan and a beta-D-(1 --> 3)-, beta-D-(1 --> 4)-'mixed linkage
' xylan co-existing in the seaweed, a fact that limits the accuracy of
the data determined. The structures of the galactan and the xylan are
similar to those previously informed for this seaweed. The antiviral
activity against four different herpes simplex viral strains and the a
nticoagulant properties of all the xylo-mannans of the system are repo
rted. (C) 1997 Elsevier Science Ltd.