P. Teesalu et al., CORRELATION OF BLUE-ON-YELLOW VISUAL-FIELDS WITH SCANNING CONFOCAL LASER OPTIC DISC MEASUREMENTS, Investigative ophthalmology & visual science, 38(12), 1997, pp. 2452-2459
Purpose. Visual field defects and changes in the optic nerve head are
signs of glaucoma, It has been shown that blue-on-yellow (B-Y) perimet
ry can reveal visual field defects earlier and shows them larger than
does white-on-white (W-W) perimetry. The Heidelberg retina tomograph (
HRT) can produce three-dimensional images of the optic disc. The aim o
f this study was to find out how B-Y perimetry results correlate with
optic disc parameters in comparison with W-W perimetry results. Method
s. One randomly chosen eye was evaluated in each of 40 normal subjects
and 37 patients with ocular hypertension and different stages of glau
coma. B-Y and W-W visual fields (program 30-2) were obtained with a Hu
mphrey perimeter. B-Y perimetry results were adjusted for the patient'
s age and lens transmission index measured with a lens fluorometer. Th
e B-Y visual field adjusted mean deviation (MD) was calculated as the
difference between the measured and expected mean sensitivity values,
predicted by the regression model fitted in normal subjects. The HRT w
ith software version 1.11 was used to acquire and evaluate topographic
measurements of the optic disc. Results. The cup shape measure showed
strongest correlation with the MD of both the B-Y and W-W visual fiel
ds. The multiple correlation coefficients from quadratic regression we
re 0.65 for both visual fields. Except for peripapillary retinal nerve
fiber layer measurements, the statistically significant correlations
of the B-Y visual field indexes with other HRT parameters were equal t
o or better than those of W-W perimetry. Conclusions. B-Y perimetry MD
s are well correlated with optic nerve head parameters measured with t
he HRT. In early stages of glaucoma, most HRT variables were better co
rrelated with the B-Y MD than with the W-W MD.