Sc. Morrison et Jk. Odonnell, IFOSFAMIDE-INDUCED ALTERATION OF TECHNETIUM-99M-DMSA RENAL PARENCHYMAL IMAGING, The Journal of nuclear medicine, 38(11), 1997, pp. 1811-1812
Renal cortical imaging with Tc-99m-dimercaptosuccinic acid (DMSA) has
become the imaging test of choice for the diagnosis of acute pyeloneph
ritis. An unusual uptake pattern was observed in a child receiving che
motherapy for a bladder rhabdomyosarcoma. Chemotherapy from ifosfamide
produces a specific pattern of injury to the renal tubule that alters
uptake of DMSA.