THE PREPARATION OF N-(1H-PYRAZOL-3-YL)ARYLAMIDES AND 1H-PYRAZOL-3-AMINES FROM POLYLITHIATED C(ALPHA),N-THIOSEMICARBAZONES AND C(ALPHA),N-SEMICARBAZONES

Authors
BEAM CF DAVIS SE CORDRAY TL CHAN KW KASSIS CM DAVIS JGF LATHAM GM GUION TS HILDEBRAN KC CHURCH AC KOLLER MU METZ CR PENNINGTON WT SCHEY KL
Citation
Cf. Beam et al., THE PREPARATION OF N-(1H-PYRAZOL-3-YL)ARYLAMIDES AND 1H-PYRAZOL-3-AMINES FROM POLYLITHIATED C(ALPHA),N-THIOSEMICARBAZONES AND C(ALPHA),N-SEMICARBAZONES, Journal of heterocyclic chemistry, 34(5), 1997, pp. 1549-1554
Citations number
47
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of heterocyclic chemistry → ACNP
ISSN journal
0022152X
Volume
34
Issue
5
Year of publication
1997
Pages
1549 - 1554
Database
ISI
SICI code
0022-152X(1997)34:5<1549:TPONA1>2.0.ZU;2-U
Abstract
C(alpha),N-Thiosemicarbazones or C(alpha),N-semicarbazones were polyli thiated with excess lithium diisopropylamide, and the resulting cycliz ed intermediates were condensed with aromatic esters to afford N-(1H-p yrazol-3-yl)arylamides. The polylithiated intermediates were also quen ched with aqueous acid to give 5-substituted, 1H-pyrazol-3-amines.