STUDIES ON ISOXAZOLE AND PYRAZOLE FORMATION BY THE REACTION OF TRIFLUOROMETHYL-SUBSTITUTED ANILINES WITH OXIME AND HYDRAZONE DIANIONS

5-(2-Aminophenyl)isoxazoles are obtained in good yields by the reactio n of 2-(trifluoromethyl) aniline with dilithio derivatives of oximes o f acetone, 3-pentanone, propiophenone, and cyclohexanone. An analogous synthesis of a substituted isoxazole from 4-(trifluoromethyl)aniline and 3-pentanone oxime and the synthesis of a substituted pyrazole from 2-(trifluoromethyl)aniline and 3-pentanone hydrazone are less efficie nt.