GLOBAL DIAGNOSTIC RATINGS COMPARED TO DSM-III-R DIAGNOSES IN EARLY DYSKINESIA

1. Two types of psychiatric diagnoses were obtained in a study of the course of early dyskinesia: DSM-III-R and Dimensional Global Ratings o f Schizophrenia, Paranoia, Mania and Depression. 2. The strength of as sociation between measures of vulnerability to developing tardive dysk inesia (TD), and clinical components from each of the two methods of o btaining psychiatric diagnoses was established by canonical correlatio ns.3. Overall, little difference was obtained between DSM-III-R catego ries and Global Ratings in terms of correlations with TD vulnerability measures. Using components from global diagnostic ratings, the Depres sion and Schizophrenia Scales made stronger contributions to the canon ical functions than Mania and Paranoia. 4. Unipolar depressed patients appear more sensitive to NL: they developed TD after less NL exposure . 5. Dimensional classification appears to be a promising approach to capturing important characteristics of psychoses.