Some vertebrates can navigate over long distances using the Earth's ma
gnetic field, but the sensory system that they use to do so has remain
ed a mystery. Here we describe the key components of a magnetic sense
underpinning this navigational ability in a single species, the rainbo
w trout (Oncorhynchus mykiss), We report behavioural and electrophysio
logical responses to magnetic fields and identify an area in the nose
of the trout where candidate magnetoreceptor cells are located. We hav
e tracked the sensory pathway from these newly identified candidate ma
gnetoreceptor cells to the brain and associated the system with a lear
ned response to magnetic fields.