Purpose: A first case of massive venous air embolism is reported as a
complication of orthotopic liver transplantation in a 17-month-old chi
ld during the dissection phase. Clinical features: During the hepatic
dissection phase, perforation of suprahepatic veins was responsible fo
r an air embolism with a decrease of PETCO2 (27 to 6 mmHg), hypoxaemia
(SpO(2) decreased from 100 to 88%), and haemodynamic instability (sys
tolic blood pressure decreased from 85 to 50 mmHg, central venous pres
sure increased from 6 to 10 mmHg). Central venous aspiration of air wa
s unsuccessful but immediate resolution occurred and neurological outc
ome was normal. Conclusion: Venous air embolism during the dissection
phase of liver transplantation in children is a risk that should be co
nsidered.