USING CELL REPLICATION DATA IN MATHEMATICAL-MODELING IN CARCINOGENESIS

Authors
PORTIER CJ KOPPSCHNEIDER A SHERMAN CD
Citation
Cj. Portier et al., USING CELL REPLICATION DATA IN MATHEMATICAL-MODELING IN CARCINOGENESIS, Environmental health perspectives, 101, 1993, pp. 79-86
Citations number
35
Categorie Soggetti
Public, Environmental & Occupation Heath","Environmental Sciences
Journal title
Environmental health perspectives → ACNP
ISSN journal
00916765
Volume
101
Year of publication
1993
Supplement
5
Pages
79 - 86
Database
ISI
SICI code
0091-6765(1993)101:<79:UCRDIM>2.0.ZU;2-W
Abstract
Risk estimation involves the application of quantitative models of dos e versus response to carcinogenicity data. Recent advances in biology, computing, and mathematics have led to the application of mathematica lly complicated, mechanistically based models of carcinogenesis to the estimation of risks. This paper focuses on two aspects of this applic ation, distinguishing between models using available data and the deve lopment of new models to keep pace with research developments.