EXOGENIC NITRIC-OXIDE DONORS AND INHIBITO RS OF ITS FORMATION (THE CHEMICAL ASPECTS)

In present review the literature data about biological role of nitric oxide, forming in vivo by enzyme oxidation of L-arginine, are generali sed. The special attention is devoted to the exogenic nitric oxide don ors - the compounds which are able to release NO in vitro and in vivo under oxidation, reduction or hydrolytic decomposition. The data about the chemical nature of the inhibitors of enzyme NO-synthase which is responsible for the nitric oxide formation from L-arginine, are also c onsidered.