The efficacy and side effects of sulphur hexafluoride (SF6) in the ref
ormation of the flat anterior chamber (AC) after standard trabeculecto
mies were studied, Ten patients with lenticulocorneal touch following
trabeculectomy were enrolled, All had water-tight conjunctival wounds
with overflowing fistulas. In 5, one to four surgical attempts to refo
rm the AC were unsuccessful. Two to seven days after trabeculectomy, t
he AC was reformed by a single injection of SF6/air mixture (20-40%).
Gas was injected through the limbus at 3 or 9 o'clock. The AC remained
deep after absorption of the gas in 2-7 days. All patients had stroma
l oedema in the first 4 days. This resolved and specular microscopy di
d not show any abnormality. After a mean follow-up of 2.5 years, all h
ad normal intraocular pressure, 3 with one topical antiglaucoma treatm
ent. Three patients developed cataracts before and 3 after reformation
of the AC. The latter 3 were not anterior capsular cataracts as induc
ed by gases. SF6/air mixture (20-40%) is inert and kind to the cornea
and, as it is absorbed in less than 7 days, it exerts minimal damage t
o the crystalline lens. It is effective in the reformation of flat ACs
.