CHEMOSELECTIVE DEBENZYLATION INVOLVING REMOVAL OF A 2-HYDROXY-1-PHENYLETHYL GROUP FROM NITROGEN

Authors
FAINS O VERNON JM
Citation
O. Fains et Jm. Vernon, CHEMOSELECTIVE DEBENZYLATION INVOLVING REMOVAL OF A 2-HYDROXY-1-PHENYLETHYL GROUP FROM NITROGEN, Tetrahedron letters, 38(47), 1997, pp. 8265-8266
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
47
Year of publication
1997
Pages
8265 - 8266
Database
ISI
SICI code
0040-4039(1997)38:47<8265:CDIROA>2.0.ZU;2-9
Abstract
In 2-(2-hydroxy-1-phenylethyl)-1-isoindolinone, selective removal of t he 2-hydroxy-1-phenylethyl group is conveniently achieved via a 3-step sequence (mesylation, elimination, hydrolysis) without breaking an en docyclic benzylic nitrogen bond. (C) 1997 Elsevier Science Ltd.