D. Kahn et al., THE FIRST 100 KIDNEY-TRANSPLANTS FROM LIVING-RELATED DONORS AT GROOTE-SCHUUR-HOSPITAL, South African medical journal, 84(3), 1994, pp. 138-141
Improved results with cadaver kidney transplantation and the increase
in the number of cadaver organs have caused the continued use of donor
kidneys from living relatives to be questioned. In this analysis of o
ur first 100 renal transplants involving a living related donor, the 5
-year graft survival rate was 70%. The 5-year graft survival rate for
recipients of grafts from HLA-identical donors was 81%, as opposed to
the 64% survival rate for grafts from one-haplotype donors. Recipients
of grafts from one-haplotype-matched donors who received donor-specif
ic blood transfusions demonstrated better graft survival than those wh
o were not transfused. This analysis demonstrates that the results of
living related kidney transplantation are good, and suggests that dono
r-specific blood transfusions may be beneficial.