Background The management of patients with concomitant coronary and ca
rotid artery disease remains a controversial subject. The aim of this
review was to develop a rational plan for the management of such patie
nts based on a review of the literature. Method and results A retrospe
ctive review was carried out of relevant papers derived from the Medli
ne database from 1964 to 1996. Conclusion The management of patients w
ith concomitant coronary and carotid artery disease has not yet been p
ut to the test in a properly designed and randomized multicentre trial
. It is suggested that, until the results of such a trial are availabl
e, the rational approach to combined symptomatic disease is combined c
arotid endarterectomy and coronary artery bypass grafting (CABG). Comb
ined surgery is also appropriate for patients with symptomatic carotid
artery disease and significant but asymptomatic cardiac disease. At p
resent there is inadequate evidence to promote carotid endarterectomy
for asymptomatic disease in combination with CABG.