SYNTHESIS OF CYTOTOXIC MAESAQUINONE BEARING A 2,5-DIHYDROXY-6-METHYL-1,4-BENZOQUINONE NUCLEUS

Authors
FUKUYAMA Y YASO H KIRIYAMA Y TAKAHASHI H MINAMI H KAMIKAWA T
Citation
Y. Fukuyama et al., SYNTHESIS OF CYTOTOXIC MAESAQUINONE BEARING A 2,5-DIHYDROXY-6-METHYL-1,4-BENZOQUINONE NUCLEUS, Tetrahedron, 53(50), 1997, pp. 16969-16976
Citations number
17
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
53
Issue
50
Year of publication
1997
Pages
16969 - 16976
Database
ISI
SICI code
0040-4020(1997)53:50<16969:SOCMBA>2.0.ZU;2-V
Abstract
A synthesis of maesaquinone -3-(Z)-10'-pentadecenyl-6-methyl-1,4-benzo quinone] has been achieved in nine steps starting from 1,4,5-trimethox ymethyloxy-2-methoxybenzene which can be readily obtained by successiv e deprotection and MOM protection of one methoxyl group of 2,5-dimetho xy-1,4-benzoquinone. (C) 1997 Elsevier Science Ltd.