SYNTHETIC STUDIES ON PENTACYCLIC AROMATIC ALKALOIDS, KUANONIAMINE-A, 11-HYDROXYASCIDIDEMIN, AND NEOCALLIACTINE ACETATE

Authors
KITAHARA Y NAKAHARA S YONEZAWA T NAGATSU M SHIBANO Y KUBO A
Citation
Y. Kitahara et al., SYNTHETIC STUDIES ON PENTACYCLIC AROMATIC ALKALOIDS, KUANONIAMINE-A, 11-HYDROXYASCIDIDEMIN, AND NEOCALLIACTINE ACETATE, Tetrahedron, 53(50), 1997, pp. 17029-17038
Citations number
22
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
53
Issue
50
Year of publication
1997
Pages
17029 - 17038
Database
ISI
SICI code
0040-4020(1997)53:50<17029:SSOPAA>2.0.ZU;2-H
Abstract
A pentacyclic aromatic alkaloid, kuanoniamine A (6) was synthesized in three steps from 6-methoxybenzothiazole-4,7-dione (8) and 2-aminoacet ophenone (9). 11-Hydroxyascididemin (4) was prepared from 5,8-quinolin edione (13, 14) or 1,4-acridinedione (20). The structure of neocalliac tine acetate, a derivative of calliactine, was determined to be 5 by t otal synthesis from 6-methoxy-5,8-quinolinedione (28) and 2-amino-5-me thoxyacetophenone (29). (C) 1997 Elsevier Science Ltd.