Nursing science continues to debate the adequacy of various philosophi
c paradigms for their ability to forward the discipline. Nursing must
embrace multiple paradigms, methodologies, and their philosophic assum
ptions to adequately address the complex and multifaceted human phenom
ena that is the focus of clinical inquiry in nursing. This article exa
mines the differences in interpretive and critical approaches to clini
cal inquiry relative to praxis, expanding how praxis can be used to in
form nursing practice. Differences in the nature of knowledge, goals o
f inquiry, and claims to praxis between the interpretive and critical
traditions are discussed. Praxis, realized through clinical inquiry in
both the interpretive and the critical paradigms, may contribute impo
rtant pieces of the puzzle to improve the human condition. Expanding t
he praxis debate challenges nurses to consider the emancipatory possib
ilities of clinical inquiry within both interpretive and critical para
digms.