A VERY CONVENIENT DIMETHYLAMINATION OF ACTIVATED AROMATIC HALIDES USING N,N-DIMETHYLFORMAMIDE AND ETHANOLAMINES

Authors
CHO YH PARK JC
Citation
Yh. Cho et Jc. Park, A VERY CONVENIENT DIMETHYLAMINATION OF ACTIVATED AROMATIC HALIDES USING N,N-DIMETHYLFORMAMIDE AND ETHANOLAMINES, Tetrahedron letters, 38(48), 1997, pp. 8331-8334
Citations number
7
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
48
Year of publication
1997
Pages
8331 - 8334
Database
ISI
SICI code
0040-4039(1997)38:48<8331:AVCDOA>2.0.ZU;2-E
Abstract
A very convenient dimethylamination of activated aromatic halides was achieved by using N,N-dimethylformamide(DMF) and ethanolamines. p-Nitr ochlorobenzene, 2-halopyridines, 2-chloroquinoline and 2-chloropyrimid ine gave the corresponding dimethylamino substituted products when tre ated with DMF and diethanolamine in 80 - 92% yield. (C) 1997 Elsevier Science Ltd.