Appearance of the large-scale instability in the magnetized slightly-i
onized gas in the Giant Molecular Clouds is discussed. Cloud gas is ch
aracterized by the fully developed small-scale magnetohydrodynamic hel
ical turbulence. The instability analysis shows that the large-scale e
ddy coherent structures may be generated in the Giant Molecular Clouds
. Characteristic scale of these structures is determined by the value
of the hydrodynamic helicity as well as joint influence of the drag fo
rce and magnetic helicity.