Bp. Mookerjee et G. Vogelsang, HUMAN HERPES VIRUS-6 ENCEPHALITIS AFTER BONE-MARROW TRANSPLANTATION -SUCCESSFUL TREATMENT WITH GANCICLOVIR, Bone marrow transplantation, 20(10), 1997, pp. 905-906
Here we report a case that presented with sudden onset of neurological
symptoms and was treated with ganciclovir. Polymerase chain reaction
analysis for human herpes virus-6 (HHV-6) from his cerebrospinal fluid
was later found to be positive. He subsequently recovered with minima
l residual neurological symptoms. Encephalitis secondary to this virus
may be more common than previously thought in patients undergoing bon
e marrow transplantation. This condition should be considered in the d
ifferential diagnosis of sudden onset neurological symptoms after bone
marrow transplantation.