R. Ghose et al., ORIGIN OF THE CORRELATION TIME-DEPENDENCE OF COHERENCE TRANSFER DISTORTIONS IN ROTATING-FRAME CROSS-RELAXATION SPECTRA, Journal of magnetic resonance [1997], 128(2), 1997, pp. 207-216
Citations number
19
Categorie Soggetti
Physics, Atomic, Molecular & Chemical","Biochemical Research Methods
HOHAHA distortions in conventional (CW) ROESY experiments are known to
be prominent when the frequency of the spin-lock field is near the mi
dpoint between the resonance frequencies of a pair of coupled spins. T
hat the disappearance of these distortions with offset from the midpoi
nt is more rapid for large molecules than smaller ones is less widely
known, and less well understood. We provide a quantitative explanation
of the latter phenomenon using a combination of theory and numerical
simulations. The cause of this effect can be found in the differential
relaxation of the various magnetization modes which are involved in H
OHAHA transfer. These modes experience enhanced relaxation far from a
Hartmann-Hahn match. This enhancement is larger for molecules Which ha
ve long correlation times. (C) 1997 Academic Press.