CARDIORESPIRATORY RESPONSE TO EXERCISE IN PATIENTS WITH EXERCISE-INDUCED BRONCHIAL OBSTRUCTION

Objective. To document the characteristics of the ventilatory response to exercise in patients with exercise-induced bronchial obstruction ( EIB). Experimental design. Comparative study during the period between December 1993 and March 1993. Setting. Ambulatory care in Ohgaki Muni cipal Hospital, Subjects and method. We evaluated 11 children with EIB . Each subject under went symptom-limited cardiopulmonary treadmill ex ercise testing (Bruce protocol).Results. Patients with EIB showed a si gnificantly lower peak oxygen consumption (peak (V) over dot O-2) than the control subjects. Three patients with EIB developed relative hypo ventilation during incremental exercise: an increase in end-tidal carb on dioxide partial pressure (PETCO2) and a decrease in (V) over dot E/ (V) over dot CO2 were observed at the end-stage of exercise testing. C onclusions. These findings demonstrate that some patients with Ern dev elope bronchoconstriction during exercise.