MELAS SYNDROME WITH ONLY STROKE-LIKE EPIS ODES

Citation
A. Drouet et al., MELAS SYNDROME WITH ONLY STROKE-LIKE EPIS ODES, Revue neurologique, 153(10), 1997, pp. 591-594
Citations number
11
Categorie Soggetti
Clinical Neurology
Journal title
ISSN journal
00353787
Volume
153
Issue
10
Year of publication
1997
Pages
591 - 594
Database
ISI
SICI code
0035-3787(1997)153:10<591:MSWOSE>2.0.ZU;2-E
Abstract
Two stroke-like episodes then a grand mal seizure occurred within nin years in a 42-year-old patient. Neuroradiological findings (CT-scan an d MRI) led to the diagnosis of incomplete MELAS syndrom. MRI with T2-w eighted images (TR: 1 000ms; TE:35ms) showed two small asignal lesions possibly resulting from hemosiderine. Metabolic studies are required to help decide on muscular biopsies. Histological findings are needed for diagnosis of this form of mitochondrial cytopathy with only stroke -like manifestations.