PATTERNING THE XENOPUS BLASTULA

Authors
Citation
J. Heasman, PATTERNING THE XENOPUS BLASTULA, Development, 124(21), 1997, pp. 4179-4191
Citations number
160
Categorie Soggetti
Developmental Biology
Journal title
ISSN journal
09501991
Volume
124
Issue
21
Year of publication
1997
Pages
4179 - 4191
Database
ISI
SICI code
0950-1991(1997)124:21<4179:PTXB>2.0.ZU;2-E
Abstract
This review starts from the classical standpoint that there are at lea st two separable processes acting with respect to axis formation and t issue specification in the early Xenopus embryo: a UV-insensitive even t establishing a postgastrula embryo consisting of three concentric ge rm layers, ectoderm, mesoderm and endoderm, all of a ventral character ; and a UV-sensitive event producing tissue of a dorsal type, includin g somites, notochord and neural tissue, and concomitantly establishing the dorsoventral and anteroposterior axes. The experimental evidence suggesting the molecular basis of the dorsal and ventral pathways is r eviewed.