A SIMPLE SYNTHESIS OF D-MYO-INOSITOL 4-PHOSPHATE AND D-MYO-INOSITOL 6-PHOSPHATE

Citation
S. Iacobucci et M. Dalarcao, A SIMPLE SYNTHESIS OF D-MYO-INOSITOL 4-PHOSPHATE AND D-MYO-INOSITOL 6-PHOSPHATE, Synthetic communications, 24(6), 1994, pp. 809-817
Citations number
14
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
ISSN journal
00397911
Volume
24
Issue
6
Year of publication
1994
Pages
809 - 817
Database
ISI
SICI code
0039-7911(1994)24:6<809:ASSOD4>2.0.ZU;2-X
Abstract
A simple synthesis of the title compounds from myo-inositol is reporte d. The procedure involves the regioselective dibutyltin oxide-promoted acylation of racemic 1,2:5,6-dicyclohexylidene-myo-inositol (2) with 1-(S)-(-)-camphanyl chloride followed by chromatographic separation of the resulting diastereomers.