FATAL METHEMOGLOBINEMIA DUE TO INHALATION OF ISOBUTYL NITRITE

Citation
Sm. Bradberry et al., FATAL METHEMOGLOBINEMIA DUE TO INHALATION OF ISOBUTYL NITRITE, Journal of toxicology. Clinical toxicology, 32(2), 1994, pp. 179-184
Citations number
22
Categorie Soggetti
Toxicology
ISSN journal
07313810
Volume
32
Issue
2
Year of publication
1994
Pages
179 - 184
Database
ISI
SICI code
0731-3810(1994)32:2<179:FMDTIO>2.0.ZU;2-O
Abstract
Isobutyl nitrite is a popular recreational drug among both homosexuals and heterosexuals as it is alleged to enhance sexual pleasure and pro long orgasm. In contrast to the ingestion of this volatile nitrite, in halation is associated only rarely with serious sequelae, though sympt omatic methemoglobinemia may occur. The case reported is the first doc umented fatality from inhalation of isobutyl nitrite. The widespread u se of isobutyl nitrite is a cause for concern and physicians should be aware of the potentially fatal consequence of abuse, particularly in those with ischemic heart disease, and its management.