PHENOTHIAZINE TREATMENT AND RESPIRATORY-DISTRESS SYNDROME IN A CHILD

An 11-year-old boy who was treated with a relatively high dose of meth otrimeprazine meleate (Levemepromazine) a phenothiazine antipsychotic drug, was admitted to the pediatric intensive care unit suffering from respiratory distress syndrome. He required intensive treatment and su pport for 13 days. The persistent effects of methotrimeprazine meleate on various organs are typical of the prolonged biological action of t he phenothiazine metabolites. The association of phenothiazine overdos e and respiratory distress syndrome merits consideration.