SURVEILLANCE OF CYTOMEGALOVIRUS AFTER SOLID-ORGAN TRANSPLANTATION - COMPARISON OF PP65 ANTIGENEMIA ASSAY WITH A QUANTITATIVE DNA HYBRIDIZATION ASSAY

Authors
BOSSART W BIENZ K WUNDERLI W
Citation
W. Bossart et al., SURVEILLANCE OF CYTOMEGALOVIRUS AFTER SOLID-ORGAN TRANSPLANTATION - COMPARISON OF PP65 ANTIGENEMIA ASSAY WITH A QUANTITATIVE DNA HYBRIDIZATION ASSAY, Journal of clinical microbiology, 35(12), 1997, pp. 3303-3304
Citations number
13
Categorie Soggetti
Microbiology
Journal title
Journal of clinical microbiology → ACNP
ISSN journal
00951137
Volume
35
Issue
12
Year of publication
1997
Pages
3303 - 3304
Database
ISI
SICI code
0095-1137(1997)35:12<3303:SOCAST>2.0.ZU;2-1
Abstract
In a multicenter study, 113 blood samples from 19 organ transplant pat ients were analyzed for cytomegalovirus by the pp65 antigenemia assay and a quantitative DNA hybridization assay. Overall, there was 84% agr eement among the results obtained by the two tests. Fifteen of 16 epis odes of active infection were detected by both assays. One episode was missed by the pp65 assay, and one patient showed significant DNA-emia but only low-level antigenemia.