D. Villar et al., TOXICITY OF MELALEUCA OIL AND RELATED ESSENTIAL OILS APPLIED TOPICALLY ON DOGS AND CATS, Veterinary and human toxicology, 36(2), 1994, pp. 139-142
Cases of melaleuca oil toxicosis have been reported by veterinarians t
o the National Animal Poison Control Center when the oil was applied d
ermally to dogs and cats. In most cases, the oil was used to treat der
matologic conditions at inappropriate high doses. The typical signs ob
served were depression, weakness, incoordination and muscle tremors. T
he active ingredients of commercial melaleuca oil are predominantly cy
clic terpenes. Treatment of clinical signs and supportive care has bee
n sufficient to achieve recovery without sequelae within 2-3 d.