SYNTHESIS OF SOME NOVEL ALPHA-CYANOKETENE S,S-ACETALS AND THEIR USE IN HETEROCYCLIC SYNTHESIS

Authors
ELGEMEIE GH ELGHANDOUR AH ELZANATE AM AHMED SA
Citation
Gh. Elgemeie et al., SYNTHESIS OF SOME NOVEL ALPHA-CYANOKETENE S,S-ACETALS AND THEIR USE IN HETEROCYCLIC SYNTHESIS, Journal of the Chemical Society. Perkin transactions. I, (21), 1997, pp. 3285-3289
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of the Chemical Society. Perkin transactions. I → ACNP
ISSN journal
0300922X
Issue
21
Year of publication
1997
Pages
3285 - 3289
Database
ISI
SICI code
0300-922X(1997):21<3285:SOSNAS>2.0.ZU;2-#
Abstract
A variety of novel alpha-cyanoketene S,S-acetals, readily prepared by the reaction of cyanoacetanilides or cyanothioacetamide with carbon di sulfide, followed by alkylation, react smoothly with nucleophiles to a fford variously substituted methylthio derivatives of pyrrole, pyrazol e, pyridine and pyrimidine.