In JP Henry's work, fighting for and losing control were important con
cepts in the interpretation of energy mobilization in psychosocial con
ditions. Attachment and support were important protective and salutoge
nic factors. These concepts have been applied in a series of epidemiol
ogical and psychophysiological real life studies. Job conditions which
force the worker to mobilize energy and concomitantly inhibit anaboli
sm could be identified at least partly by means of the demand-control-
support model originally proposed by Karasek. The most adverse conditi
ons at work arise when psychological demands are high and at the same
time the decision latitude is low. This combination is associated with
changes in the regulation of endocrine parameters as well as with inc
reased morbidity-heart disease, functional gastrointestinal symptoms a
nd musculoskeletal disorders. Examples of studies of physiological cor
relates of psychosocial processes leading to fight for control are als
o described from outside work activities.