This paper deals with the implementation of a non elitist genetic algo
rithm with roulette wheel selection for tile synthesis of separation s
equences. After a brief recall of problem combinatorics, the coding st
rategy based on the notion of stack for separating a list of elements
with feasability constraints, as well as the genetic operators used, a
re detailed A didactic example is first presented for estimating the n
umerical values of the algorithm basic parameters, and then two large
scale examples concerning the separation of mixtures involving 14 and
16 hydrocarbons by means of distillation sequences, are reported The o
btained results, compared with those given by a simulated annealing pr
ocedure and a purely random search, clearly show the genetic algorithm
efficiency.