PREVIOUS INTRAVENOUS CHEMOTHERAPY DOES NOT ALTER RESPONSE RATE OR SURVIVAL-TIME OF PATIENTS WITH HEPATIC METASTASES FROM COLORECTAL-CANCER TREATED BY HEPATIC-ARTERY CHEMOTHERAPY
Dl. Morris et al., PREVIOUS INTRAVENOUS CHEMOTHERAPY DOES NOT ALTER RESPONSE RATE OR SURVIVAL-TIME OF PATIENTS WITH HEPATIC METASTASES FROM COLORECTAL-CANCER TREATED BY HEPATIC-ARTERY CHEMOTHERAPY, Australian and New Zealand journal of surgery, 67(11), 1997, pp. 796-797
Background: The present paper addressed the issue of whether pretreatm
ent with intravenous (IV) chemotherapy affects response rate or surviv
al in patients receiving hepatic artery chemotherapy (HAC). Methods: C
ase note reviews of 164 patients treated in a teaching hospital from J
une 1990 to July 1996 were carried out. Results: The response rate and
carcino-embryonic antigen (CEA) fall in the two groups was almost ide
ntical. There was a nonsignificant survival advantage in the non-pretr
eatment group. Conclusions: Previous administration of IV chemotherapy
did not affect the CEA response of patients receiving HAC.