Background The full circuit of common atrial flutter using conventiona
l methods of sequential or multielectrode activation mapping is not co
mpletely understood. Methods and Results We performed three-dimensiona
l right atrial endocardial activation mapping during common counterclo
ckwise atrial flutter in 17 patients (16 men, 1 woman; mean age, 53+/-
11 years) by using the Cordis-Biosense EP Navigation system and assess
ed the distribution of estimated conduction velocities and double and
fractionated potentials. ECG flutter wave morphologies were compared w
ith activation patterns. Points (91+/-29) were sequentially acquired c
overing 88+/-11% of the flutter cycle length of 239+/-22 ms. A wide an
d variable posterior zone of double and fractionated potentials coinci
ded with blocking and colliding wave fronts and formed the posterior l
imit of the circuit. A progressively widening septal (sep) wave front
ascending from just beyond the coronary sinus ostium, passed cranially
as a broad front anterior to the superior vena cava (SVC) in 14 patie
nts, whereas fusion around the SVC formed the superior (sup) limb of t
he circuit in 3. Bounded anteriorly by the tricuspid valve, the wave f
ront descended down the lateral (lat) aspect of the right atrium befor
e completing the circuit in all cases through the inferior vena cava-t
ricuspid annulus isthmus. The estimated conduction velocity in the med
ial isthmus (0.6+/-0.3 m/s) was lower than in the other limbs of the c
ircuit (sup=1+/-0.5 m/s, lat=1+/-0.5 m/s, sep=0.9+/-0.4 m/s, P=.05). D
ouble and fractionated potentials were constant and more prevalent in
the posterior right atrium. ECG flutter wave morphology did not correl
ate with three-dimensional activation maps. Conclusions Interindividua
l variations occur in the right atrial circuit of common atrial flutte
r, with constant activation through the cavotricuspid isthmus. A varia
ble zone of block forms the posterior limit. Fusion around the SVC can
occur, and ascending medial septal activation does not follow a consi
stent pattern.