H. Johansson et al., EXERCISE TESTS IN LARGE GROUPS OF CHILDREN ARE NOT A SUITABLE SCREENING-PROCEDURE FOR UNDIAGNOSED ASTHMA, Allergy, 52(11), 1997, pp. 1128-1132
Schoolchildren (n=473), 12-13 years of age, from five schools, and wit
hout known asthma, participated in a screening test for exercise-induc
ed asthma (EIA). The children were tested in large groups of 10-15 pup
ils. Peak expiratory flow (PEF) was measured before, immediately after
, and 6-8 min after 6 min of running exercises in a gymnasium. A fall
in PEF of at least 10% on two separate test occasions was considered a
n abnormal result. Children with abnormal results were given an asthma
questionnaire and then tested individually in hospital with a standar
dized exercise test measuring FEV1, PEF, and flow/volume curve. In the
screening test, 23 (4.9%) of the 473 children had an abnormal result.
When tested in hospital, five (1%) children had a decrease in PEF and
/or FEV1 of at least 10% (10-14%) after exercise. Furthermore, three o
f these five children had a history indicating mild EIA. We conclude t
hat the use of PEF measurement as a screening method for EIA in large
groups of schoolchildren cannot be recommended because it yields many
false-positive results.