A RETROSPECTIVE REVIEW is presented of 20 patients with traumatic brai
n injury who were treated during the course of their illness by lobect
omies either after a herniation or other significant deterioration or
to reduce elevated intracranial pressure. All the patients suffered fr
om blunt head trauma. Patient ages ranged from 19 to 59 years (average
, 34 yr). The initial Glasgow Coma Scale score ranged from 3 to 15 (av
erage, 8.2). There were 14 frontal lobectomies, 2 temporal, 3 frontal
and temporal, and 1 occipital. Surgery was performed between 0 and 8 d
ays after injury (average, 2.8). Outcome was favorable (good or modera
tely disabled) in 11 patients and unfavorable (severely disabled, pers
istently vegetative, or dead) in 9. No patients survived in a persiste
ntly vegetative state. A higher initial Glasgow Coma Scale score was p
ositively correlated with a more favorable outcome (P < 0.03). Younger
patients also showed a significant positive relationship to outcome (
P < 0.0005). Better pupillary reactivity showed a significant trend to
ward a more favorable outcome (P < 0.04). The type of lesions identifi
ed on computed tomographic scans had no association with outcome. A lo
bectomy can be a useful adjuvant in the management of severe brain inj
ury, especially in younger patients with relatively higher initial Gla
sgow Coma Scale scores who subsequently deteriorate or develop elevate
d intracranial pressure.