We report the successful surgical treatment of a large and painful leg
ulcer associated with systemic sclerosis (scleroderma). In addition,
there was a long occlusion of the superficial femoral artery and ankle
systolic blood pressure was 80 mmHg (ankle-brachial-index 0.65). All
conservative treatments including systemic antibiotics, nifedipine, in
travenous iloprost, intravenous penicilline G and hyperbaric oxygen fa
iled. Pain was intolerable and below-knee amputation was consered In a
first attempt to save the limb, the patient underwent femoropopliteal
bypass surgery. Despite a successful outcome of the bypass operation
and normalization of the ankle blood pressure, the large wound remaine
d recalcitrant and extremely painful. A second attempt to save the lim
b consisted of complete debridement of all sclerotic tissue down to th
e fascia and split skin grafting. The graft took in over 90% of the su
rface and the remaining wound healed spontaneously. Large leg ulcers i
n systemic sclerosis can become limb threatening. Radical debridement
combined with a split skin graft seems to be a promising way to avoid
amputation.