SYNTHESIS AND CHARACTERIZATION OF BINARY AND HETEROBIMETALLIC COMPLEXES OF DITHIOFUROATE WITH 3D-METAL IONS

New complexes [M(dtf)(2)] (M = Mn-II or Cu-II), Cr(dtf)(3) and V(dtf)( 4) dtf = dithiofuroate and heterobimetallic complexes. M[Cd(dtf)4] (M = VO2+, Mn-II, Fe-II, Co-II, Ni-II or Zn-II) have been prepared in H2O -EtOH and characterized by elemental analyses, magnetic susceptibility measurements and spectroscopic studies. The known complexes Fe(dtf)(3 ), Co(dtf)(3), Ni(dtf)(2), and Zn(dtf)(2) have been screened towards t he bacteria Pseudomonas spergillus and Bacillus spergillus. In vitro r esults of the binary complexes on P-815 (murine mastocytoma) indicate that these complexes show significant inhibition of [H-3]thymidine and [H-3]uridine incorporation in DNA and RNA in the tumour cells.