Efforts to find antimicrobial agents which are effective against vanco
mycin-resistant enterococcus have been unsuccessful. One promising ant
ibiotic, quinupristin/dalfopristin, has, however, been used with a suc
cess rate of approximately 60%. Other antibiotics are under investigat
ion. Prevention is the best policy for the control of vancomycin-resis
tant enterococcus and includes contact isolation, the cohorting of pat
ients, the appropriate use of vancomycin and education of patients and
staff.