G. Eckerwall et al., METAPHYSEAL HISTOLOGY AND MAGNETIC-RESONANCE-IMAGING IN LEGG-CALVE-PERTHES-DISEASE, Journal of pediatric orthopedics, 17(5), 1997, pp. 659-662
Cylindrical biopsy specimens from the proximal femoral metaphysis were
obtained in conjunction with surgery in 22 patients with Legg-Calve-P
erthes disease. The histopathological examination revealed fat necrosi
s, vascular proliferation, and focal fibrosis indicating previous epis
odes of ischemia. Then was no correlation between the histopathologica
l findings and the corresponding magnetic resonance images.