INDOCYANINE GREEN ANGIOGRAPHY IN CENTRAL SEROUS CHORIORETINOPATHY - ICG ANGIOGRAPHY IN CSC

Purpose. To analyse images obtained by indocyanine green angiography i n central serous chorioretinopathy (CSC). Methods. Ninety patients aff ected with CSC were examined using indocyanine green angiography. Resu lts. CSC was detected in 127 of the 180 eyes examined. Leakage points were detected in 99 eyes with fluorescein angiography; in 85 of these eyes, they corresponded to hyperfluorescence with indocyanine green an giography, while a hyperfluorescence of the neuroepithelial detachment was seen in 21 eyes. Areas of choroidal hyperpermeability were seen i n all 127 eyes with CSC and in 9 fellow eyes. With ICG angiography, th e appearance of pigment epithelial detachments was similar to that pre viously described (early hyperfluorescence and later hypofluorescence) , and was seen in 47 eyes. In 103 eyes, hypofluorescent lesions of var ious sizes, were detected which became more marked in the later stages . These lesions corresponded to retinal pigment epithelium lesions in fluorescein angiography, mainly hyperfluorescence caused by window def ect. We were also able to observe RPE atrophic tracts in 31 eyes. Thes e tracts appeared hyperfluorescent in 11 eyes where a minimal amount o f RPE atrophy was present and hypofluorescent in 20 eyes in which the tract had marked RPE atrophy. Conclusion. The results obtained confirm the finding of choroidal hyperpermeability and subretinal diffusion o f ICG, which indicate involvement of the choroid in CSC. The observati on of progressively hypofluorescent lesions corresponding to retinal p igment epithelium alterations suggests that there may be as yet unknow n interactions of pigment epithelium and ICG.