ASYMMETRIC CONSTRUCTION OF 4H-CARBAZOL-4-ONE INTERMEDIATES VIA THE CYCLOHEXADIENONE ANNULATION OF CHIRAL CARBENE COMPLEXES

Authors
QUINN JF POWERS TS WULFF WD YAP GPA RHEINGOLD AL
Citation
Jf. Quinn et al., ASYMMETRIC CONSTRUCTION OF 4H-CARBAZOL-4-ONE INTERMEDIATES VIA THE CYCLOHEXADIENONE ANNULATION OF CHIRAL CARBENE COMPLEXES, Organometallics, 16(23), 1997, pp. 4945-4947
Citations number
22
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear
Journal title
Organometallics → ACNP
ISSN journal
02767333
Volume
16
Issue
23
Year of publication
1997
Pages
4945 - 4947
Database
ISI
SICI code
0276-7333(1997)16:23<4945:ACO4IV>2.0.ZU;2-K
Abstract
The quaternary carbon in a 4H-carbazol-4-one can be introduced with hi gh stereoprecision. in the cyclohexadienone annulation of a 2-indolyl chromium carbene complex bearing an imidazolidinone chiral auxiliary. The chiral complex 12 teas found to exist as atropisomers that were re adily separated, and each was found to react with the same alkyne to g ive opposite configurations at the quaternary carbon in the H-4-carbaz ol-4-one product.