SERUM OXALATE MICROASSAY USING CHEMILUMINESCENCE DETECTION

Determination of serum oxalate concentration is important for the diag nosis and monitoring of hyperoxalurias, and extends to patients with a ll types of renal disease. Approximately 5 to 10 ml of blood is requir ed for each test by conventional methods, and the test is not adapted for use in children. We developed a highly sensitive method that limit s the volume of blood required for the test. This new and sensitive to ol to detect H2O2 can be successfully substituted for the conventional , and expensive, colorimetric reaction to accurately analyze oxalate c oncentration.