Background: Adrenal tumors of more than 6 cm diameter, also called mac
rotumors, cause diagnostic and therapeutic problems. Aim: To perform a
n analysis of adrenal macrotumors diagnosed by CAT scan between 1984 a
nd 1995. Patients and methods: Thirty three patients aged 9 to 86 year
s old, 15 female, with an adrenal macrotumor diagnosed by CAT scan, we
re analyzed. Results: Thirty percent of tumors were functioning (70% s
ecreted cathecolamines and 30% cortisol). Eighty two percent had an ad
renal localization and 48% were para-adrenal. thirty four percent were
malignant. These tumors were mostly non functioning, 70% occurred in
men and 67% were metastatic. Conclusions: Most adrenal macrotumors in
this series were non functioning and 36% were malignant.