OBJECTIVE To identify a management approach for Group A streptococcal
(GAS) pharyngitis that would address overuse of antibiotics and could
be implemented immediately. QUALITY OF EVIDENCE No randomized, control
led trials were found; four observational studies met our criteria: si
mplicity, discrimination ability for GAS pharyngitis compared with thr
oat culture, and validation in a different patient population. Only on
e scoring system fulfilled all three criteria. MAIN FINDINGS Formal cl
inical scoring systems have the potential to improve family physicians
' ability to identify and manage GAS pharyngitis. One system had been
sufficiently validated to support its use in clinical practice. Four c
linical characteristics (no cough, fever higher than 38 degrees C, exu
date, and tender cervical nodes) linked to explicit management decisio
ns form the basis for a sore throat score. CONCLUSIONS Use of a clinic
al score for management of GAS pharyngitis can be recommended on the b
asis of the rarity of rheumatic fever in modern society, the resources
devoted to management of upper respiratory tract illnesses, the volum
e of antibiotics prescribed, and the emergence of antibiotic resistanc
e as a growing health issue.