To introduce a duplex PCR system consisting of the STR loci D21S11 and
HUMFIBRA in forensic identity testing we analysed a Dutch Caucasian d
atabase of 205 individuals. The combined power of discrimination of th
e two loci is 0.9978 and there was no evidence for linkage equilibrium
between the two loci (p = 0.91). However, we noticed departure from H
ardy-Weinberg equilibrium for the D21S11-locus in our database (p = 0.
03), but the differences between observed and expected D21S11 allele p
air frequencies were of negligible practical significance in forensic
calculations.