A DUTCH POPULATION STUDY OF THE STR LOCI D21S11 AND HUMFIBRA

Citation
A. Ovington et al., A DUTCH POPULATION STUDY OF THE STR LOCI D21S11 AND HUMFIBRA, International journal of legal medicine, 110(1), 1997, pp. 14-17
Citations number
15
Categorie Soggetti
Pathology
ISSN journal
09379827
Volume
110
Issue
1
Year of publication
1997
Pages
14 - 17
Database
ISI
SICI code
0937-9827(1997)110:1<14:ADPSOT>2.0.ZU;2-S
Abstract
To introduce a duplex PCR system consisting of the STR loci D21S11 and HUMFIBRA in forensic identity testing we analysed a Dutch Caucasian d atabase of 205 individuals. The combined power of discrimination of th e two loci is 0.9978 and there was no evidence for linkage equilibrium between the two loci (p = 0.91). However, we noticed departure from H ardy-Weinberg equilibrium for the D21S11-locus in our database (p = 0. 03), but the differences between observed and expected D21S11 allele p air frequencies were of negligible practical significance in forensic calculations.