FREQUENCIES OF THE 5 PCR-BASED GENETIC-MARKERS LDLR, GYPA, HBGG, D7S8AND GC IN THE POPULATION OF ASTURIAS (NORTH SPAIN)

Allele and genotype frequencies of the loci LDLR, GYPA, HBGG, D7S8 and GC (PM loci) were investigated in a population sample of 215 unrelate d individuals from Asturias (North Spain). Multiplex amplification and simultaneous typing of the five loci was carried out using the polyma rker PCR amplification and typing kit. All loci met Hardy-Weinberg exp ectations. The Asturian sample does not differ significantly from othe r Caucasians, but significant differences were observed between this p opulation and SW Hispanic, Afro-american and Korean populations.