SYNTHESIS AND NMR-STUDIES OF KEY INTERMEDIATES TO A NEW CLASS OF BETA-LACTAM - THE TRINEMS

Authors
MARCHIORO C PENTASSUGLIA G PERBONI A DONATI D
Citation
C. Marchioro et al., SYNTHESIS AND NMR-STUDIES OF KEY INTERMEDIATES TO A NEW CLASS OF BETA-LACTAM - THE TRINEMS, Journal of the Chemical Society. Perkin transactions. I, (4), 1997, pp. 463-468
Citations number
34
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of the Chemical Society. Perkin transactions. I → ACNP
ISSN journal
0300922X
Issue
4
Year of publication
1997
Pages
463 - 468
Database
ISI
SICI code
0300-922X(1997):4<463:SANOKI>2.0.ZU;2-7
Abstract
An efficient synthesis of the four isomeric epoxides 4a-d, key compoun ds to the trinem ring system, starting from )-(+)-4-acetoxy-3-[1'-(ter t-butyldimethylsilyloxy) ethyl]azetidin-2-one 6a is described. All the intermediates have been characterized by means of NMR techniques.