Wl. Homan et al., COMPARISON OF THE INTERNAL TRANSCRIBED SPACER, ITS-1, FROM TOXOPLASMA-GONDII ISOLATES AND NEOSPORA-CANINUM, Parasitology research, 83(3), 1997, pp. 285-289
The internal transcribed spacer (ITS1) region and the 5' part of the 5
.8S ribosomal RNA gene of the ribosomal DNA repeat from 20 Toxoplasma
gondii isolates was sequenced and found to be identical in all isolate
s, independent of host origin or virulence to mice. The ITS1 region fr
om the closely related coccidian parasite Neospora caninum differed in
22% of its nucleotides. Hence, the ITS1 region provides a good marker
for the distinction of T. gondii and N. caninum but is not useful for
epidemiology studies of T. gondii.